In 1821 Thomas de Quincy described his experiences of opium abuse in his book Confessions of an English Opium Eater. Later, morphine was used widely as a painkiller during the American Civil War, but many veterans became addicted. In 1875, chemists trying to find a less addictive form of morphine made heroin. At first, no-one realised how addictive heroin was - it was used in cough mixture. Addiction to heroin is now a serious problem in many parts of the world.