Early microtome, England, 1825-1835
This type of microtome was devised by Andrew Pritchard (1804-1882) to cut thin sections of wood. The date of the invention is uncertain, although research suggests that it pre-dates 1835. This microtome was designed to cut slices of wood. Attached to a piston screw, which moves the sample up and down, the piece of wood is cut in slithers by a double-handled knife. This is the first type of microtome made to be screwed to the edge of a table so it does not move during the cutting operation.
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The study of the structure of tissues by means of special staining techniques combined with light and electron microscopy.
The use of microscopes to study objects or samples. The three major types of microscopy are optical, electron and scanning probe microscopy.
An instrument used to cut thin sections of biological material so that they can be examined under a microscope.