Thalomid (thalidomide) capsules, United States, 1999
Marketed as a treatment for leprosy, HIV infections and some forms of bone marrow cancers, thalidomide is a drug with a chequered history. In the late 1950s and early 1960s, thalidomide was given to pregnant women to help ease morning sickness. The drug actually caused thousands of serious birth defects across the world, four hundred of those occurring in the United Kingdom. Babies were born with under-developed or missing limbs and for this reason the drug was withdrawn from use in 1962. In the following years those affected by the drug fought a long battle for compensation. Today the drug is used under strictly controlled conditions. Celgene Corporation, which made and donated the drug to the Science Museum’s collections, had Thalomid approved for use by the American Food and Drug Administration in 1998.
Related Themes and Topics
There are 188 related objects. View all related objects
Techniques and Technologies:
A chronic disease that affects the skin, mucous membrane and nerves. It is now confined mainly to the tropics and is transmitted by direct contact. Previously a widely feared disease, leprosy is not highly infectious.
Human Immunodeficiency Virus (HIV) is a virus that weakens vital cells in the immune system, and leads to AIDS. There are two strands: HIV-1, which leads to immunity suppression; and HIV-2, which is not as potent and is only common in West Africa. HIV is spread through direct contact with bodily fluids.
Any cancerous tumour. It arises from the abnormal and uncontrolled division of cells which then invade and destroy the surrounding tissues. Cancer cells spread and can form secondary tumours some distance from the original.
A drug that was prescribed in the 1950s and 60s as a sedative for pregnant women. Thalidomide was supposed to relieve symptoms of morning sickness. However, it led to birth defects among babies, and was banned. Since 1998, the drug has been avaliable to treat other conditions, but its prescription is highly regulated.