Interfering with transmission
Most neurones communicate with others by releasing one of over 50 different types of neurotransmitter. Each neurotransmitter fits on to its receptor on the surface of the neighbouring neurone. Chemicals that interfere with the signalling may act on the neurotransmitter or on the receptor. Many of these are natural substances, such as nerve poisons produced by plants and animals for self-defence or capturing prey. Others, including nerve gases are man-made substances.