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Huntington disease

People with Huntington disease suffer from jerky, random movements, and spasms of their limbs, neck and body. Other symptoms include changes in mood, personality and memory. An area of the brain gradually wastes away as the disease progresses, including part of the basal ganglia. This seems to cause a loss of control of movements: muscles normally held in check start contracting randomly.

A woman with Huntington disease.
A woman with Huntington disease.
Conor Caffrey/Science Photo Library

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