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How is sickle-cell disease inherited?

Sickle-cell disease affects people who inherit two copies of an altered gene from their carrier parents. Carrier parents have a one-in-four chance of having an affected child and a one-in-two chance of having a child who is an unaffected carrier. Carriers of sickle cell are not affected themselves, as they have a working gene as well as an altered gene.

Inheritance of sickle-cell disease.
Inheritance of sickle-cell disease.

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